The S-enantiomer of ibuprofen is responsible | vedclass

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(A) To determine the $(S)$-configuration of ibuprofen,we assign priorities to the groups attached to the chiral carbon atom using the Cahn-Ingold-Prel

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Vedclass · Answer

(A) To determine the $(S)$-configuration of ibuprofen,we assign priorities to the groups attached to the chiral carbon atom using the Cahn-Ingold-Prelog $(CIP)$ sequence rules: $1$. $-COOH$ group (priority $a=1$) $2$. Phenyl group (priority $b=2$) $3$. $-CH_3$ group (priority $c=3$) $4$. $-H$ atom (priority $d=4$) For the $(S)$-configuration,when the lowest priority group $(d=4)$ is pointing away from the viewer (on a dashed bond),the sequence from priority $1$ $\rightarrow 2$ $\rightarrow 3$ must be counter-clockwise. In structure $A$,the $-H$ atom is on a solid wedge (pointing towards the viewer). If we look at the sequence $1$ $\rightarrow 2$ $\rightarrow 3$,it appears clockwise,but because the lowest priority group is towards us,the actual configuration is $(S)$. Alternatively,looking at the provided solution image,the structure shows the $-COOH$ group as priority $a$,the phenyl group as $b$,the $-CH_3$ group as $c$,and the $-H$ atom as $d$ on a dashed bond. The path $a$ $\rightarrow b$ $\rightarrow c$ is counter-clockwise,confirming the $(S)$-configuration.

Column-$I$	Column-$II$
$A$. Acetaldehyde,vinyl alcohol	$1$. Enantiomers
$B$. Eclipsed and staggered ethane	$2$. Tautomers
$C$. $(+)$$2$-butanol,$(-)$$2$-butanol	$3$. Chain isomers
$D$. Methyl-$n$-propylamine and diethylamine	$4$. Conformational isomers
	$5$. Metamers

$A$. Acetaldehyde,vinyl alcohol	$1$. Enantiomers
$B$. Eclipsed and staggered ethane	$2$. Tautomers
$C$. $(+)2$-butanol,$(-)2$-butanol	$3$. Chain isomers
$D$. Methyl-$n$-propylamine and diethylamine	$4$. Conformational isomers
	$5$. Metamers

The $S$-enantiomer of ibuprofen is responsible for its pain-relieving properties. Which one of the following structures shown below is $(S)$-ibuprofen?

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Consider the following structures. Which statement is $NOT$ correct?

Match the following:
$A$. Acetaldehyde,vinyl alcohol $1$. Enantiomers
$B$. Eclipsed and staggered ethane $2$. Tautomers
$C$. $(+)2$-butanol,$(-)2$-butanol $3$. Chain isomers
$D$. Methyl-$n$-propylamine and diethylamine $4$. Conformational isomers
$5$. Metamers

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