The reaction is fastest when X isR-C(=O)-X + | vedclass

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(A) The reaction is a nucleophilic acyl substitution reaction.In this reaction,the leaving group ability of $X^-$ determines the rate of the reaction.

Vedclass · Accepted Answer

$Cl$

Vedclass · Answer

(A) The reaction is a nucleophilic acyl substitution reaction.In this reaction,the leaving group ability of $X^-$ determines the rate of the reaction.$A$ better leaving group makes the reaction faster.Leaving group ability is inversely proportional to the basicity of the group.Since $Cl^-$ is the weakest base among the given options (because its conjugate acid $HCl$ is the strongest acid),it is the best leaving group.Therefore,the reaction is fastest when $X$ is $Cl$.

The reaction is fastest when $X$ is
$R-C(=O)-X + Nu^- \rightarrow R-C(=O)-Nu + X^-$

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The reaction is fastest when $X$ is$R-C(=O)-X + Nu^- \rightarrow R-C(=O)-Nu + X^-$