Which of the following is the most reactive?

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(D) The order of reactivity of acid derivatives towards nucleophilic acyl substitution reactions is: $RCOCl > (RCO)_2O > RCOOR' > RCONH_2$. This order

Vedclass · Accepted Answer

Acetyl chloride

Vedclass · Answer

(D) The order of reactivity of acid derivatives towards nucleophilic acyl substitution reactions is: $RCOCl > (RCO)_2O > RCOOR' > RCONH_2$. This order is determined by the leaving group ability; the reactivity decreases as the basicity of the leaving group increases. The leaving groups are $Cl^-$,$RCOO^-$,$RO^-$,and $NH_2^-$. Since $Cl^-$ is the weakest base,it is the best leaving group,making $Acetyl \ chloride$ $(RCOCl)$ the most reactive.

Similar Questions

Which of the following does not give an alcohol with $NaBH_4$?

The compound that does not give the iodoform test is

In the esterification reaction of alcohols with carboxylic acids,which of the following occurs?

$CH_3COOC_2H_5$ with excess of $C_2H_5MgBr$ and hydrolysis gives:

Which one of the following orders of acid strength is correct?

Vedclass Test Series

Exam Paper Generator

Online Exam Module