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(B) The first clinical gene therapy was performed in $1990$ on a $4$-year-old girl with adenosine deaminase $(ADA)$ deficiency.$ADA$ deficiency is cau

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Adenosine deaminase deficiency

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(B) The first clinical gene therapy was performed in $1990$ on a $4$-year-old girl with adenosine deaminase $(ADA)$ deficiency.$ADA$ deficiency is caused by the deletion of the gene for adenosine deaminase,which is crucial for the proper functioning of the immune system.In this therapy,lymphocytes from the patient's blood were grown in a culture outside the body,and a functional $ADA$ $cDNA$ was introduced into these lymphocytes using a retroviral vector.These genetically engineered lymphocytes were then returned to the patient's body.

List-$I$	List-$II$
$A. \alpha-1$ antitrypsin	$I. \text{Cotton bollworm}$
$B. \text{Cry } IAb$	$II. ADA \text{ deficiency}$
$C. \text{Cry } IAc$	$III. \text{Emphysema}$
$D. \text{Enzyme replacement therapy}$	$IV. \text{Corn borer}$

The first clinical gene therapy was given for the treatment of .........

Similar Questions

An example of gene therapy is

In which bacteria was the insulin gene cloned?

Which of the following methods,other than gene therapy,has been used for the treatment of $ADA$ deficiency?

Which enzyme was targeted during the first clinical gene therapy given in $1990$ to a $4$ year old girl?

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