What is the meaning of $Bio-patents$?

The two polypeptide chains of human insulin are linked together by which of the following?

Identify the correct statement.

In $1983$, Eli Lilly, an American company, prepared two $DNA$ sequences corresponding to $A$ and $B$ chains of human insulin and introduced them in plasmids of which organism to produce insulin chains?

In $1983$,Eli Lilly,an American company,first prepared two $DNA$ sequences corresponding to $A$ and $B$-chains of human insulin and introduced them into the plasmids of $Escherichia$ $coli$ to produce insulin chains. Chains $A$ and $B$ were prepared separately,extracted,and combined by creating:

In which bacteria was the insulin gene cloned?