Write a note on the cyclic structure of glucose.

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(N/A) The open-chain structure of glucose fails to explain certain reactions,such as the fact that glucose does not form a Schiff's base with ammonia and does not give a $2,4-DNP$ test. This led to the proposal of a cyclic structure.
In the cyclic structure,the $-OH$ group at $C-5$ reacts with the aldehydic group at $C-1$ to form a six-membered hemiacetal ring,also known as a pyranose ring.
This reaction results in the formation of two anomeric forms of glucose:
$1$. $\alpha-D-(+)-glucose$: In this form,the $-OH$ group at $C-1$ is on the right side.
$2$. $\beta-D-(+)-glucose$: In this form,the $-OH$ group at $C-1$ is on the left side.
These two forms are called anomers,and the $C-1$ carbon is known as the anomeric carbon.

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